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In a 4-week study in type 2 diabetes patients, weekly administration of up to 70 mg efruxifermin reduced triglycerides by 6070%, non-HDL-cholesterol by about 35%, fasting insulin about 50%, and fasting glucose about 20% compared to baseline, while increasing HDL-cholesterol by 60% and adiponectin by about 95% (246)

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9,10 In 1978, Rutter proposed new diagnostic criteria for autism emphasizing social skill dysfunction, language and communication impairment, and repetitive behaviours as three aspects of the basic criteria, abandoning the special skills and attractive appearance of Kanners criteria

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