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10.1038/s41577-018-0066-7

Shen-shuai-II-recipe inhibits tubular inflammation by PPAR-mediated fatty acid oxidation to attenuate fibroblast activation in fibrotic kidneys

2.3.4 Epigenetic regulation in the immune-metabolic interactive network In the immune-metabolic interactive regulatory network of PH, epigenetic mechanisms serve as key hubs connecting metabolic abnormalities and immune imbalance through DNA methylation, histone modification, and noncoding RNA regulation