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Ikeda Y, Komura M, Watanabe M, Minami C, Koike H, Itoh S et al

This approach aims to achieve early detection, early intervention, and early treatment, ultimately reducing mortality rates and improving the prognosis and quality of life for patients with CNDs

A linear gradient of buffer A (99.9% water, 0.1% formic acid) and buffer B (99.9% acetonitrile, 0.1% formic acid) was used at a flow rate of 700 L/min, wherein the B% ramped from 5% to 45% in 3.5 min

Both global ROS scavengers (TEMPOL) and mitochondria-specific antioxidants (MitoQ, CAT) can reduce mtROS levels, inhibit PAECs proliferation, and attenuate hypoxia-induced PH (Suresh et al., 2018