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Populations (Moghadam et al., 2018)

Bmal1 deficiency can lead to genomic instability, increased oxidative stress, and cell cycle imbalance, thereby promoting cancer development and accelerating aging through its capacity to enhance mTORC1 activity (Khapre et al., 2014a)

The week-by-week timeline below is derived from rat studies where researchers sacrificed animals at specific intervals and examined tissue histologically