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Maytansines or their derivatives maytansinoids inhibit cell proliferation by inhibiting the microtubules formation during mitosis through inhibition of polymerization of tubulin {see, e.g., Remillard et al

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Beloranib may also cause robust weight loss and hypophagia in rats with hypothalamic and genetic obesity (235)

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doi: 10.1038/s41419-024-07059-w

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