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The antioxidant effect of N-acetylcysteine ameliorates oxidative stress and inflammatory response in COVID-19

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Note however that a well resolved viral infection, without associated persisting symptoms, also creates an immunological scar with persisting immune activation and increased cytokine production several months after symptom resolution (130, 131)

336,337 For example, oxidation of Cys292 and Cys361 on ATG4B hinders its capacity to degrade the microtubule-associated protein 1A/1B light chain 3 (LC3), leading to a disruption in autophagic flux

The pericytes and astrocytes of the neurovascular unit surround the abluminal side of brain capillary endothelial cells, providing extra structural and functional support