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Nishida Y, Ishizawa J, Ayoub E, Patsilevas T, Ostermann L, Heinz Montoya R, Muftuoglu M, Ruvolo V, Mak PY, Tao W, Carter BZ, Kojima K, Daver N, Lesegretain A, Seki T, Shacham S, Konopleva M, and Andreeff M

Protein carbonylation (PC), a major hallmark of OS, is an irreversible modification that can be generated by covalent addition of lipid peroxidation products known as reactive lipid aldehydes (RLAs) into proteins, resulting in protein inactivation, misfolding, aggregation, degradation and formation of neo-antigens

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