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Recent quercetin co-crystal developments include four new systems: quercetin:caffeine, quercetin:caffeine:methanol, quercetin:isonicotinamide, and quercetin:theobromine dihydrate, each demonstrating superior pharmacokinetic properties (237)

9.11 Antiviral applications of probiotics A critical appraisal of the evidence supports probiotic interventions against a range of clinically significant viral infections, including SARS-CoV-2, viral upper respiratory tract infections (URTIs), influenza, viral hepatitis, human immunodeficiency virus (HIV), and human papillomavirus (HPV) (480, 481)

To induce abnormal intestinal barrier function, the present study used LPS to disrupt the tight junction between epithelial cells

Furthermore, existing studies have not adequately distinguished the relative contributions of transcriptional upregulation of GPX4 versus increased protein stability to the outcomes, leaving some mechanistic explanations still at the inferential level