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Less common but serious side effects include pancreatitis, gallbladder issues, and (in rare cases) thyroid tumors in patients with a personal or family history of medullary thyroid cancer or MEN-2

Szabo, G., Thursz, M

Pros Directly supports ATP (energy) production Helps reduce levels of methylmalonic acid, a marker of B12 deficiency Supports nerve cell health and myelin repair Cons Very unstable and not always available in oral supplements Harder to find and often more expensive Still needs careful formulation to ensure absorption Best for : People struggling with chronic fatigue, mitochondrial dysfunction, or symptoms of energy burnout