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To assess the translational efficiency of the PRKAA1 5UTR in shCtrl cells, FLuc activity was divided by RLuc activity in the 5UTR reporter group and normalized to that of the empty reporter group to calculate relative luciferase activity

Abrams SL, Evangelisi C, Chiarini F, Misaghian N, Basecke J, Millela M, Tafuri A, Libra M, Stivala F, Konopleva M, Andreeff M , Steelman LS, Troppmair J, Martelli AM, McCubrey JA

These platforms link anthracyclines to monoclonal antibodies against tumor-specific antigens, such as HER2 , allowing precise delivery of the cytotoxic payload