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bioRxiv, 2024

Side Effects : Low doses - mild cortical arousal & deferral of fatigue High doses - convulsions, cardiac arrhythmias, death Because of the high morbidity and mortality associated with theophylline-induced seizures, treatment of seizures should be rapid and aggressive

High feverespecially during the first trimesterhas been associated with adverse outcomes, including neural tube defects and miscarriage