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Peripheral neuropathy that results from vitamin B 12 deficiency is one of the rarer causes of OH

Treatment options can include: Supplements Oral B12 : Effective for most people, even those with mild malabsorption Sublingual B12 : Dissolves under the tongue, dominantly orally with some absorption passing into the bloodsteam Injectable B12: Used in specific cases, for example if someone is not responding to oral or sublingual supplements

If the total volume received will exceed 100 mL in 12 hours, then it is prohibited and a Therapeutic Use Exemption (TUE) may be required

It's also noteworthy that B12 supplementation repressed the expression of certain skin proteins in studies, leading to alterations in skin health