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When multiple studies conducted by different researchers in different countries all point in the same direction, the conclusion is far more robust than any single trial

The WNT pathway, which is often involved in tumorigenesis signaling, is crucial for tumor angiogenesis

While other immunotherapies such as Arevirumab-3 succeeded in providing complete immunity against fatal Lassa fever, this monoclonal antibody cocktail has only been tested in non-human primates and rendered ineffective against the evolving Lassa virus lineage [302]

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