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Janevski M, Antonas KN, Sullivan-Gunn MJ, McGlynn MA, Lewandowski PA (2011) The effect of cocoa supplementation on hepatic steatosis, reactive oxygen species and LFABP in a rat model of NASH

When oxidative stress is left unchecked, it can lead to the formation of harmful substances that damage blood vessels, contributing to conditions like atherosclerosis and high blood pressure

Strategies such as combining copper ionophores with ferroptosis inducers, or superimposing DSF/Cu regimens on a background of GSH depletion or p53 activation, could overcome resistance to single-death modalities and deliver a potent ferroptosis-cuproptosis double punch to OSCC