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Reported reactions include injection-site redness/itch, transient flushing and histamine-type reactions

Beyond POTS, autonomic dysfunction in long COVID can present as: Dysregulated sweating Impaired gastrointestinal muscle contractions, causing constipation, pain, nausea, or weight loss Temperature dysregulation An exaggerated fight-or-flight response The vagus nerve within this systemthe primary parasympathetic nerve connecting the brain to the gut, heart, and lungsappears to be particularly vulnerable to COVID-19-related damage, with implications for heart rate variability, gut function, and the inflammatory regulatory role the vagus nerve normally performs

activating the genes that build this matrix matters for structural repair

Research suggests it plays a role in modulating the hypothalamus, influencing neurotransmitters such as GABA, serotonin, dopamine, and noradrenaline