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Shaking creates mechanical stress and shearing forces that can break the fragile peptide bonds, rendering it useless
These systems also protect fragile antigenic materials from enzymatic breakdown within the body, ensuring that the immune system encounters them in their active form
To further complicate matters, the study states: "no clear optimal [pH range] was seen when the test was run without [fatty acid byproduct]." It was only used to compare how animal and human skin metabolises the form of vitamin A naturally present in the skin, not about how topical vitamin A (retinol) benefits the skin
