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177 Hormones like estrogen and relaxin can alter the synthesis and degradation of collagen, affecting its density, cross-linking, and alignment

Because we previously reported that old C57BL/6J mice and older adults share many age-associated abnormalities [14,22,64], these mice were an ideal to conduct our investigation of cognitive decline and brain abnormalities in aging

Both reactions are fundamental to cellular energy metabolism

Recently, a plethora of studies have shown that ferroptosis also plays a critical role in a variety of pathophysiological processes such as ischemic organ injury, stroke, cardiac myopathy, and neurodegenerative diseases