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Acute promyelocytic leukemia (APL) is caused by a genetic lesion that disrupts the alpha retinoic acid receptor (RAR-alpha) gene found on the long arm of chromosome 17 and the PML gene found on chromosome 15

Conclusion: The BIRDIE index may be an accurate and comparable estimator of LCC across cases

Since clusters of ALS patients have been found in certain geographical areas, researchers have searched for an underlying environmental theme such as heavy metal poisoning

et al., 2011) and glioblastoma cells to temozolomide (Johannessen et al., 2013) and ALKBH8 -knockout in mouse embryonic fibroblasts elevates ROS levels that could promote DNA damage ( E