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Description

GXS: Glyoxalic acid synthetase

Expression levels of S100A8 and S100A9 are significantly elevated in psoriatic keratinocytes and leukocytes, and their expression levels correlate positively with the severity of psoriasis (107)

Authors information YO, HA, SY and MM were the researchers in the same laboratory and cooperatively carried out the study

Excessive iron accumulation in cells can generate ROS through the Fenton reaction, leading to lipid peroxidation ( GPX4 is a critical regulator in preventing ferroptosis, as it inhibits ferroptosis by catalyzing the reduction of lipid peroxides ( Figure 1 )