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Free mtDNA, ROS, and the MAVS pathway are required for the recruitment of NLRP3 to mitochondrial membranes

coli mutants, and incubated at 21C for 20 hours

Other research results report that the CB 2 receptor agonist HU308 reduces the production of ROS-generating enzymes NOX4, NOX2, and NOX1, as well as subsequent renal oxidative stress in mice (Zhang et al., 2009)