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Further, CO-treated mice showed reduced thiobarbituric acid (TBA)-reactive substances and cytokine-induced neutrophil chemoattractant 1 (CINC-1) expression in colonic mucosa, as compared with TNBS-air treated mice (75)

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First-strand cDNA was synthesized using Superscript III first-strand synthesis kit (Invitrogen)

Overall, with appropriate patient selection, dosing, and monitoring (periodic IGF-1 testing, glucose monitoring in at-risk individuals, clinical assessment), Sermorelin appears to have a favorable benefit-to-risk profile for addressing GH deficiency or age-related GH decline