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This was accompanied by upregulation of inducible nitric oxide synthase (iNOS), IL-1, and TNF-, and downregulation of arginase 1 (Arg-1), IL-10, and transforming growth factor-beta (TGF-)

There are direct preventive effects of LA in the early stage of AFLD development

[DOI] [PMC free article] [PubMed] [Google Scholar] 17.Taquet M., et al

The 1-desaturase TMEM189 is upregulated and promotes breast and other cancers by inhibiting autophagy-regulated ferroptosis, and its inhibition is a potential therapeutic treatment