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Indeed, a recent review explicitly notes that bacteria exposed to plant-derived phytochemicalsincluding OSCsmay evolve resistance through general stress-response mechanisms such as efflux pump upregulation, enzymatic detoxification, or metabolic remodeling under sublethal exposures (Vaou et al., 2021)

Patients often tell me they feel fine on their first consultation, only to recognise in hindsight, once their B12 has been corrected, that they had been running at a reduced baseline for years

Reduccin de la hiperpigmentacin inducida por estrs oxidativo El estrs oxidativo causado por la exposicin a los rayos UV, la contaminacin y la inflamacin puede estimular los melanocitos y desencadenar un exceso de produccin de melanina, lo que provoca manchas oscuras y un tono desigual

& Trope, C