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Mechanistically, lanosterol administration increased the solubility of lens proteins and reduced oxidative stress by enhancing total antioxidant capacity and decreasing GSSG/GSH ratio in the lens cortex (150), and its effect was dependent on the severity of the condition or the lanosterol concentration in aqueous humor which varies from 0 to 31.61 ng/ml (150,153)

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In vitro and in vivo sequestration of phencyclidine by Me(4) cucurbit[8]uril

This cellular priming provides the mechanistic foundation for FOXO4-DRI's selective targeting, enabling researchers to eliminate senescent cells without affecting healthy tissue function