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This indicated that the increased CYSS levels might originate from auto-oxidation of CYS, which easily takes place out of the cell under normoxic conditions ( Given the fact that no GSH or GSSG was detected in the stomach and small intestinal digesta of control animals, the finding that GSSG was recovered from the gastrointestinal lumen in the LGSH and HGSH group could demonstrate the oxidation of GSH in the gastrointestinal tract

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