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Indeed, aged garlic extract was shown to have more potent antiglycation properties compared to fresh garlic extract

They exhibited increased intraocular pressure and mydriasis, degeneration of retinal ganglion cells, optic nerve head excavation and reduction in optic nerve thickness, generalized severe irregularity of retinal vessels, faint presentation of choroidal vessels, and severe optic nerve disc atrophy

Looking ahead, improving tissue- or cell-specific vector targeting, building high-throughput screening platforms for FAD-sensitive variants, and using patient-derived iPSC neurons for personalized preclinical testing will be pivotal in transitioning from experimental use to clinical implementation of integrated nutrient plus gene-editing therapies

However, its essential to be aware of the risks, such as potential overdoses, especially with fat-soluble vitamins