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Following traumatic brain injury or ischemic stroke, excessive microglial activation contributes to secondary injury through release of inflammatory mediators and reactive oxygen species

(1) Adrenal Gland Basics Small, triangular shaped organs that sit on top of the kidneys Produce vital hormones like cortisol, aldosterone, DHEA, androgenic steroids, epinephrine (adrenaline), and norepinephrine (noradrenaline) Regulate metabolism and support energy levels Support cardiovascular function Regulate normal immune system function Maintain blood pressure Manage the bodys stress response Regulate blood sugar levels Help manage inflammatory processes The adrenal glands are designed to manage the stress response

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Pharmacol Res 173:e105874