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Description

However, the pathological mechanisms underlying cerebral ischemia reperfusion injury (CIRI) after CPR are very complex and involve calcium overload, mitochondrial dysfunction, inflammatory responses, apoptosis, the accumulation of oxygen free radicals, and the excessive release of excitatory amino acids[19]

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This underlines the intricate involvement of CER in the regulation of iron-related cellular processes and its role in mitigating ferroptosis responses in HCC cells

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