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Published: August 11, 2016 Copyright: 2016 Ueberschlag et al

Glomus tumor of the digits

In contrast, the trimeric GATOR1 protein complex consisting of DEPDC5 (DEP domain-containing 5), NPRL2 (nitrogen permease regulator-like 2), and NPRL3 (nitrogen permease regulator-like 3) functions as a GAP for RagA, and promotes GTP hydrolysis upon AA insufficiency via a poorly understood mechanism (Shen et al., 2018)