chac1 glutathione Human Protein Degrades Glutathione, and mRNA Induction Is Regulated by the Transcription Factors ATF4 and ATF3 and a Bipartite ATF/CRE Regulatory Element* Frontiers | CHAC1: a master

Frontiers CHAC1: a master regulator of oxidative stress and ferroptosis in human diseases and cancers Mitochondrial respiratory function is preserved under cysteine starvation via glutathione catabolism in NSCLC Nature Communications CHAC1 degradation of glutathione enhances cystine starvation induced necroptosis and ferroptosis in human triple negative breast cancer cells via the GCN2 eIF2 ATF4 pathway Oncotarget Long noncoding RNA GDIL acts as a scaffold for CHAC1 and XRN2 to promote platinum resistance of colorectal cancer through inhibition of glutathione degradation Cell Death & Disease

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