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Among lymphocytes, CD8 + T cells are particularly sensitive to cholesterol depletion, as low cholesterol levels hinder their proliferation and induce autophagy-mediated apoptosis

7.4.2 Community-engaged intervention design Effective interventions require understanding and respecting local contexts: Participatory research: Engage food processors, vendors, and consumers in identifying barriers to safer practices and co-designing culturally acceptable solutions

After NF-B translocates into the nucleus, it promotes the transcription of inflammatory genes such as ICAM-1 and E-selectin, which not only disrupts mitochondrial function but also leads to metabolic disorders (62)