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COPD: Histamine levels and mast cell activation cause bronchial constriction in COPD.[ref][ref] Tinnitus and Menieres: A genetic variant in the H4 receptor increases the risk of Menieres and ringing in the ears

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Conclusion: This study unveils a new role of HU in alleviating diabetic kidney disease by modulating inflammation and apoptosis through the mTOR-S6K pathway