glutathione reaction disulfide Is Required to Regulate the Formation of Native Bonds within Proteins Entering the Secretory Pathway* reduced oxidized glutathione Glutathione Disulfide

Since the upregulation of these phase-II detoxification enzymes regulated in part by the transcription factor, Nrf2, provides cellular protection from oxidative stress, we next asked whether exposure of microglia to various forms of -synuclein enabled an antioxidant response

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It is better understood as a significant vulnerability factor that interacts with genetics, stress exposure, and neuroinflammation to influence mood regulation