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"While we acknowledge your response that an abrupt shortening of the enrollment period led to challenges and mistakes, your response is inadequate because, regardless of the length of the enrollment period, you are still responsible for ensuring that subjects meet protocol-specified eligibility criteria before you enroll them into the study," said FDA

Being deficient in vitamins and minerals, such as zinc, iron, selenium, magnesium, and iodine, may also make symptoms such as fatigue worse

1992;56(Suppl 5):12881290

Oxidative stress occurs when there is a severe imbalance between the production of harmful free radicals and the brain's natural antioxidant defense mechanisms