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We assessed the effect of fiber supplementation on the gut microbiota and gene abundance of the enzyme cutC, a key enzyme for microbial TMA formation, a precursor for TMAO

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...Ultimately, investigation of long-term use of Q10 in dogs with MMVD and heart diseases of other etiologies are therefore relevant -- preferably with dosing tailored in accordance with laboratory testing of Q10 plasma concentrations." * Pharmacokinetics is the study of the movement of drugs in the body, including the processes of absorption, distribution, localization in tissues, biotransformation, and excretion