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This loss: Slows resting metabolism by 2-4% per decade Increases injury risk from reduced stability Accelerates bone density loss (muscle and bone health are linked) Contributes to the soft appearance even at a healthy weight Makes everyday activities progressively more difficult The Hormonal Challenge Testosterone, the primary muscle-building hormone, is present in women at about 1/10th the level of men

This, in turn, prompts the pituitary gland to release more growth hormone into the bloodstream

Competing interests All authors declared the absence of any financial or personal conflicts pertaining to this work

Long-Term Follow-up of Hematopoietic Stem-Cell Gene Therapy for Cerebral Adrenoleukodystrophy