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High-risk groups include individuals with functional or anatomic asplenia, HIV infection, leukemia, lymphoma, Hodgkins disease, multiple myeloma, generalized malignancy, chronic kidney failure, nephrotic syndrome, or other immunosuppressive conditions

4.1 Effects on the male reproductive system Melatonin significantly improves the status of the male reproductive system, acting through the hypothalamicpituitarygonadal (HPG) axis to regulate the secretion of reproductive hormones, primarily GnRH and luteinizing hormone (LH) (71)

Factors such as temperature, light, and humidity can affect the stability of peptides, making proper storage essential

PMid:32819927 PMCid:PMC7440823 Castelli MC, Friedman K, Sherry J, et al