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doi: 10.1016/S0190-9622(99)70182-9

More fat burned = glycogen spared = longer time to fatigue Especially beneficial for CrossFit, endurance athletes, and metabolic conditioning MOTS-c improves physical performance by regulating mitochondrial respiration and metabolic substrate use. Reynolds et al., Nature Communications Supports Anti-Aging and Stress Resistance Emerging research suggests that MOTSc acts like a mitochondrial stress hormone , improving longevity pathways similar to caloric restriction