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Burwinkel B, Kreuder J, Schweitzer S, Vorgerd M, Gempel K, Gerbitz KD, Kilimann MW: Carnitine transporter OCTN2 mutations in systemic primary carnitine deficiency: a novel Arg169Gln mutation and a recurrent Arg282ter mutation associated with an unconventional splicing abnormality

Other studies found that TMAO induces hypercholesterolemia by promoting intracellular CHO accumulationenhancing macrophage cholesterol accumulation via microbiota-dependent pathways involving the increased expression of pro-atherogenic scavenger receptor proteins CD36 and SRA on the cell surface (Wang et al., 2011)

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This dietary pattern is a nutritional model that aims to improve the damaged intestinal microbiota and is used in ASD, ADHD, depression, dyspraxia, dyslexia, schizophrenia, obsessive compulsive disorder, epilepsy, bipolar disorder, and many other conditions that affect brain functions [83]