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1903 The Wright brothers achieve the first controlled, sustained powered flight, forever changing transportation and exploration

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8 Where results are unclear, serum MMA and homocysteine levels (both of which accumulate with B12 deficiency as discussed above) can also be used to confirm a diagnosis, although homocysteine is not specific to B12 deficiency, as it may also be caused by deficiencies in other B vitamins

However, sensitivity was only 50% for carcinogenic and 67% for mutagenic NAs, due to their inability to detect the known carcinogens S-NNN and NMA