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National Health and Nutrition Examination Survey found that higher dietary selenium intake in adults aged 65 and older was associated with better performance on cognitive tests assessing memory, processing speed and executive function, indicating a potential protective effect against age-related cognitive decline

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12 Investigation gaps and approaching perspectives Despite significant progress, there still needs to be more in our understanding of the mechanisms through which probiotics, prebiotics, and synbiotics exert their effects on digestive enzymes, oxidative stress, and antioxidant defense in fish

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