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Risks and Unknowns Remaining research gaps include: Long-term systemic administration data Optimal dosing strategies outside dermatology Interaction with copper metabolism disorders Comparative efficacy versus standard wound treatments Most evidence supports local, tissue specific effects rather than systemic transformation

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Researchers have also explored its influence on fibroblast proliferation , angiogenesis , and gene expression regulation with studies suggesting it may interact with over 4,000 human genes involved in tissue repair and inflammatory response