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As with all GLP-1 agonists, long-term post-marketing surveillance will be essential to characterize the pancreatic safety profile with greater statistical precision, particularly for rare events such as acute pancreatitis (estimated background rate of approximately 35 per 100,000 person-years in the general population) and the theoretical concern about pancreatic cancer

To model and study ECD induced by these mechanical stimuli, a variety of in vitro flow-loading and stretch loading devices have been developed

Lack of nicotinate could lead to a variety of diseases, such as enteritis, dermatitis, neuroinflammation [66]

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