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In comparison, the rate of HCC of spontaneously cleared HCV patients with NAFLD or AUD was 0.15 and 0.33 per 100 patient-years, respectively, with age 55 years, elevated baseline ALT and AST and FIB-4 1.45 as significant risk factors in univariable and multivariable analyses for both the latter cohorts

They showed a significant decrease in the expression of FSH receptor, activin, and androgen receptor genes as the DZN concentration increased

Previous studies have found a close relationship between human gut microbes and UC, and may be the most important measure of UC for clinical judgment