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As discussed above, ()-Phen is a highly potent inhibitor of AChE (IC 50 = 22-36 nM) in plasma and brain, as are its N1-nor and N1,N8-bisnor metabolites [74]

It is also important to point out that each study has its limitations, whether it is a small sample size which reduces the statistical power of the study (32, 36, 4851), heterogeneity of COPD patients enrolled in the studies such as grouping of subjects with different GOLD stages into one group, as in a study by Pierrou et al

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Alguns usurios utilizam combinaes com outros compostos, porm qualquer protocolo deve ser definido por profissional qualificado.