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This resistance was mitigated by transiently transfecting NRF2 siRNA or stably overexpressing KEAP1 in both in vitro and xenograft models (107)

10.1038/onc.2013.260 70 HaapamkiM

In: Lal R (ed) Encyclopedia of Soil Science, 3rd edn

However, these approaches often have side effects, for example, sedation, anticholinergic effects, metabolic alterations, weight gain, and involuntary movements, and do not target the pathology or the main symptoms of ASD (27)