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Methods: A retrospective observational study was conducted on 400 patients with AF (20192021)

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The 3ml size offers greater flexibility than smaller vials while avoiding unnecessary excess, making it suitable for moderate-duration protocols or multiple reconstitutions

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Furthermore, while biological agents targeting specific inflammatory pathways have demonstrated promising clinical outcomes, approximately 3050% of patients either fail to respond initially or develop neutralizing antibodies that diminish therapeutic effectiveness over time

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