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Preclinical studies have confirmed that targeted ferroptosis inhibition alleviates renal injury and fibrosis: 1) deferoxamine mitigates 5/6 nephrectomy-induced CKD in rats via iron metabolism and TGF-1/Smad3 pathway modulation (191)

doi: 10.1016/j.devcel.2024.03.034 286 ZhouL.LianH.YinY.ZhengY.-S.HanY.-X.LiuG.-Q.et al

Ion fluxes leading to an increase in local pH have been observed in several systems and could be induced by elicitation from avirulent Hessian fly larval elicitors

Keywords: uterine myomas, progestin, gonadotropin-releasing hormone receptor blockers, selective progesterone receptor modulators, antiestrogens Introduction Uterine leiomyomata (myomas, fibroids) are the most common gynecological disorder