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Ultrastructurally, three types of cytoplasmic inclusions have been described: dense reticulated substance in the dilated cisternae of rough endoplasmic reticulum, fine granular substance in rough endoplasmic reticulum, and nonmembrane bound dense granulofibrillar in the cytoplasm (Helyer and Petrelli 1978)

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We hypothesized that enhanced caspase-1 expression in the sensitized differentiated urothelium would lead to a more robust pyroptotic cell death response upon wild type (WT) (HlyA+) UPEC infection in vitro

Until a few years ago, some patients were thought to have so-called non-secretory myeloma