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[Abstract]2024 Jun 21;20(6):e1012305

The effects of APE on intracellular ROS and RNS were also determined using flow cytometry

They also may activate platelets

It may even contribute to certain health conditions, including cancer, heart disease, and diabetes ( Promisingly, studies show that piperine could possess powerful anti-inflammatory properties to help keep chronic inflammation at bay ( For instance, one test-tube study showed that piperine extract helped protect skin cells against ultraviolet (UV)-induced skin damage and inflammation ( In another test-tube study, piperine blocked the production of several markers of inflammation in brain and spinal cord cells ( Several older animal studies also suggest that piperine could reduce inflammation associated with conditions like arthritis and asthma ( However, further research is needed to determine how piperine supplements, including BioPerine, affect inflammation in humans